{"id":90,"date":"2021-04-15T17:32:56","date_gmt":"2021-04-15T15:32:56","guid":{"rendered":"http:\/\/eurotau.fr\/?page_id=90"},"modified":"2021-10-23T14:06:35","modified_gmt":"2021-10-23T12:06:35","slug":"programme-eurotau-oct-25","status":"publish","type":"page","link":"https:\/\/eurotau.fr\/?page_id=90","title":{"rendered":"Programme Eurotau Oct. 25"},"content":{"rendered":"\n<p class=\"has-large-font-size\"><strong>Welcome address: <\/strong><\/p>\n\n\n\n<p>8:30-9:00 &#8211; Luc Bu\u00e9e and RCF  representative<\/p>\n\n\n\n<p><strong>9:00-11:00 Session 1<\/strong> (Chairs: A. Rovelet-Lecrux &amp; J. Attems)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>9:00 &#8211; Anne Rovelet-Lecrux (France) <em>Clinical and neuropathological diversity of tauopathy in MAPT duplication carriers<\/em> <\/li><li>9:10 &#8211; Roberto Simone &#8211; Rohan de Silva (UK) <em>Natural antisense transcripts containing an embedded mammalian-wide interspersed repeat repress MAPT translation and aid proteostasis in neurodegeneration<\/em><\/li><li>9:20 &#8211; Johannes Attems (UK) <em>Tau in ageing\/ AD\/ PART and frontotemporal lobar degeneration<\/em> <\/li><li>9:35 &#8211; Tiago Gil Oliveira (Portugal) <em>Primary age-related tauopathy (PART) and Alzheimer\u2019s disease show differential magnetic resonance imaging atrophy patterns<\/em><\/li><li>9:45 &#8211; Bernard Hanseeuw (Belgium) <em>[F18]-MK6240 positron emission tomography to image tau aggregates in Alzheimer&#8217;s disease and other tauopathies<\/em> <\/li><li>9:55 &#8211; Ruiqing Ni (Switzerland) <em>High-resolution non-invasive whole brain optoacoustic tomography imaging of tau in P301L tauopathy mice<\/em><\/li><li>10:05 &#8211; Eugeen Vanmechelen (Belgium) <em>Two plasma p-tau SIMOA-based assays using a shared synthetic calibrator peptide for detection of AD pathology<\/em><\/li><li>10:15 &#8211; Pieter J Visser (The Netherlands) <em>Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity processes in\u00a0 AD<\/em><\/li><li>10:25 Questions<\/li><li>10:40 Flash-talks<ul><li>Georgie Lines  (UK) <em>Investigating proteostasis  in development and disease  using iPSC-neurons with MAPT mutations linked to FTD<\/em><\/li><li>Isabelle Paiva (France) <em>Dysregulation of the cholesterol pathway laters epigenomic signatures of hippocampal neurons in AD<\/em><\/li><li>Engie Prifti (Greece) <em>The two cysteine residues of tau protein are functionally distinct and contribute differentially to its pathogenicity in vivo<\/em><\/li><\/ul><\/li><\/ul>\n\n\n\n<p><em>11:00-11:30 Coffee break<\/em><\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>11:30-13:00 <a rel=\"noreferrer noopener\" href=\"https:\/\/rainwatercharitablefoundation.org\/rainwater-prize\" target=\"_blank\">Rainwater Prize ceremony<\/a><\/strong> <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>11:30 &#8211; <em>Introduction<\/em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/li><li>11:35 &#8211; Richard Carmona &#8211; <em>Prize overview<\/em> <\/li><li>11:50 &#8211;  Philippe Amouyel (Chairperson: L Bu\u00e9e) &#8211; <em>JPND &amp; European funding for NDD<\/em><\/li><li>12:15 &#8211; Celeste Karch,  Rainwater Prize for Innovative Early Career Scientist \u00a0(Chair: Leonard Petrucelli)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/li><li>12:30 &#8211; David Holtzman, Rainwater Prize forOutstanding Innovation in Neurodegenerative Disease Research \u00a0(Chairperson: Howard Feldman)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/li><li>12:45 &#8211;  Todd Rainwater\u00a0<em>thanks winners, nominators, scientists<\/em><\/li><li>12:55 &#8211; Amy Rommel\u00a0&#8211;\u00a0<em>About prize &amp; nominations open<\/em><\/li><li>12:59 &#8211;  Luc Buee closes the Rainwater Ceremony<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"469\" src=\"https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-1024x469.jpg\" alt=\"\" class=\"wp-image-340\" srcset=\"https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-1024x469.jpg 1024w, https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-300x137.jpg 300w, https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-768x351.jpg 768w, https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-1536x703.jpg 1536w, https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM-1568x718.jpg 1568w, https:\/\/eurotau.fr\/wp-content\/uploads\/2021\/06\/Rainwater-Prize-logo-Final-TM.jpg 1914w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><em>13:00-14:15 Lunch &amp; Poster exhibition<\/em><\/p>\n\n\n\n<p><strong>14:15-16:00 Session <\/strong>2 (Chairs: A. Rommel &amp; L. Bu\u00e9e)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>14:15 &#8211; David Holtzman, 2020 Rainwater Prize forOutstanding Innovation in Neurodegenerative Disease Research  (USA)<\/li><li>14:35 &#8211; Michel Goedert, 2019 Rainwater Prize forOutstanding Innovation in Neurodegenerative Disease Research (UK) <em>Cryo-EM structures of amyloid filaments from human brai<\/em>n<\/li><li>14:55 &#8211; Celeste Karch, 2020 Rainwater Prize for Innovative Early Career Scientist (USA) <em>Molecular and cellular drivers of tauopathy<\/em><\/li><li>15:15 &#8211; Mathieu Bourdenx (France) <em>Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis<\/em><\/li><li>15:25 &#8211; Wiep Scheper (The Netherlands) <em>Cell type-specific proteostatic responses to tau pathology<\/em><\/li><li>15:35 &#8211; Lukasz A Joachimiak (USA) <em>DnaJC7 binds natively forlded structural elements in tau to inhibit amyloid formation<\/em><\/li><li>15:45 &#8211;  Questions<\/li><\/ul>\n\n\n\n<p><em>16:00-16:30 Coffee break<\/em><\/p>\n\n\n\n<p><strong>16:30-18:15 Session 3<\/strong> (Chairs: I. Landrieu &amp; Y. Fichou)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>16:30 &#8211; Illana Gozes (Israel) <em>Novel insights to ADNP\/NA\/Tau protein interactions dictating brain development and aging<\/em><\/li><li>16:40 &#8211; Cl\u00e1udio M. Gomes (Portugal) <em>Dynamic interactions and Ca<sup>2+<\/sup>-binding modulate the chaperone activity of S100B preventing tau aggregation and seeding<\/em><\/li><li>16:50 &#8211; Romain La Rocca (France) <em>Three zinc binding sites of Tau and their role in tau aggregation<\/em><\/li><li>17:00 &#8211; Amandine Grimm (Switzerland) <em>Abnormal tau protein disturbs the endoplasmic reticulum \u2013 mitochondria coupling and intracellular cholesterol homeostasis<\/em><\/li><li>17:10 &#8211; Yann Fichou (France) <em>Tau intertwines with cofactors: how it modulates complex phase separation, oligomerization &amp; aggregation propertie<\/em>s <\/li><li>17:20 &#8211; Marina Rierola (Germany) <em>Tau shapes microtubule-dependent transport in the dendrites&nbsp;<\/em><\/li><li>17:30 &#8211; Laura Vall\u00e9s Saiz (Spain) <em>Tau expression in the kidney: cell distribution and physiological function<\/em><\/li><li>17:40 &#8211; Marie Galas (France) <em>Revisiting the link between tau and the neuronal cell cycle in Alzheimer\u2019s disease: an unexpected role for nuclear tau<\/em><\/li><li>17:50 &#8211; Mahmoud Maina (UK \/ USA)<em> The involvement of Tau in nucleolar function and stress response<\/em> <\/li><li>18:00 &#8211; Questions<\/li><\/ul>\n\n\n\n<p>18:15-20:00 Rainwater Prize reception (OPEN to all Eurotau participants)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Welcome address: 8:30-9:00 &#8211; Luc Bu\u00e9e and RCF representative 9:00-11:00 Session 1 (Chairs: A. Rovelet-Lecrux &amp; J. Attems) 9:00 &#8211; Anne Rovelet-Lecrux (France) Clinical and neuropathological diversity of tauopathy in MAPT duplication carriers 9:10 &#8211; Roberto Simone &#8211; Rohan de Silva (UK) Natural antisense transcripts containing an embedded mammalian-wide interspersed repeat repress MAPT translation and&hellip; <a class=\"more-link\" href=\"https:\/\/eurotau.fr\/?page_id=90\">Continue reading <span class=\"screen-reader-text\">Programme Eurotau Oct. 25<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-90","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/90","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/eurotau.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=90"}],"version-history":[{"count":38,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/90\/revisions"}],"predecessor-version":[{"id":474,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/90\/revisions\/474"}],"wp:attachment":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=90"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}