{"id":93,"date":"2021-04-15T17:33:09","date_gmt":"2021-04-15T15:33:09","guid":{"rendered":"http:\/\/eurotau.fr\/?page_id=93"},"modified":"2021-10-23T14:08:12","modified_gmt":"2021-10-23T12:08:12","slug":"programme-eurotau-oct-26","status":"publish","type":"page","link":"https:\/\/eurotau.fr\/?page_id=93","title":{"rendered":"Programme Eurotau Oct. 26"},"content":{"rendered":"\n<p class=\"has-large-font-size\"><em>Preliminary programme &#8211; some changes may occur<\/em><\/p>\n\n\n\n<p><strong>8:30-9:00 &#8211; Plenary lecture<\/strong><\/p>\n\n\n\n<p class=\"has-normal-font-size\"><strong>Kenneth Kosik<\/strong> (USA) <em>A Rite of Passage: Tau&#8217;s Route Between And Within Cells<\/em><\/p>\n\n\n\n<p><strong>9:00-11:00 &#8211; <strong>Session 4 (Chairs: <\/strong><\/strong>A. Mudher &amp; I. Ferrer<strong><strong>)<\/strong><\/strong><\/p>\n\n\n\n<ul class=\"has-normal-font-size wp-block-list\"><li>9:00 &#8211; Eckhard Mandelkow (<em>S. Wegmann<\/em>) (Germany) <em>Recent insights into Tau seeding and phosphorylation<\/em><\/li><li>9:15 &#8211; Susanne Wegmann (Germany) <em>Condensating the interactions of tau<\/em><\/li><li>9:25 &#8211; Louise Serpell (UK) <em>The role of the core of tau paired helical filaments in AD and other tauopathies<\/em><\/li><li>9:35 &#8211; Davide Tampellini (France) <em>Enhancement of synaptic stimulation induces tau clearance via the autophagosomal\/lysosomal pathway<\/em><\/li><li>9:45 &#8211; Amrit Mudher (UK) <em>Tau aggregation and spread of pathology in\u00a0Drosophila<\/em><\/li><li>9:55 &#8211; Isidre Ferrer (Spain) <em>Importance of host tau in tau seeding and spreading in tauopathies<\/em><\/li><li>10:10 &#8211; Diane Hanger (UK) <em>Truncated tau as a model of human tauopathy<\/em> <\/li><li>10:25 &#8211;  Marc Dhenain (France) <em>Induction of tau lesions in amyloid-bearing mice and in primates after inoculation of Alzheimer brain extracts<\/em> <\/li><li>10:35 &#8211; Questions<\/li><\/ul>\n\n\n\n<p><em>10:50-11:20 Coffee break<\/em><\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>11:20-13:00 <a rel=\"noreferrer noopener\" href=\"https:\/\/rainwatercharitablefoundation.org\/rainwater-prize\" target=\"_blank\">Session 5<\/a><\/strong> (Chairs: D. Hanger &amp; I. Sotiropoulos)<\/p>\n\n\n\n<ul class=\"has-normal-font-size wp-block-list\"><li>11:20 &#8211; Delphine Boche (UK) Neuroinflammation, peripheral immune cells and tau pathology in FTLD-tau<\/li><li>11:30 &#8211; Michael Heneka (Germany-Luxembourg) <em>How microglia modulate tau pathology<\/em><\/li><li>11:45  &#8211; Karine Cambon (France) <em>Neuronal Tau pathology transfers to astrocytes and induces their loss according to Tau aggregation state in mouse models<\/em><\/li><li>11:55 &#8211; Kevin Richetin (Switzerland) <em>Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer\u2019s disease<\/em><\/li><li>12:05 &#8211; Ioannis\/John Sotiropoulos (Portugal) <em>A novel method of spontaneously-released extracellular vesicles isolation from mouse and human brain<\/em><\/li><li>12:15 &#8211; Elodie Leroux (France) <em>Extracellular vesicles and tau seeding among tauopathies<\/em><\/li><li>12:25 &#8211; Karen Duff (UK) <em>New cell model for FTD tauopathy<\/em><\/li><li>12:40 &#8211; Questions<\/li><li>12:55 &#8211; Flash talks<ul><li>AC Sandhof (Germany)  <em>A new C. elegans model for intercellular tau  spreading discovers novel modifyers of tau propagation<\/em><\/li><li>Lauren VC Miller (UK) <em>Tau seeded aggregation occurs in a non-linear manner in organotypic slice cultures and&#8230;<\/em><\/li><li>Neil S Donison (Canada) The role of LRRK2 in the phosphorylation of Tau (Thr175) associated with TBI<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><em>13:15-14:30 Lunch &amp; Poster exhibition<\/em><\/p>\n\n\n\n<p><strong>14:30-16:00 Session <\/strong>6 (Chairs: S. Wegmann &amp; M. Dhenain)<\/p>\n\n\n\n<ul class=\"has-normal-font-size wp-block-list\"><li>14:30 &#8211; Eliana Nachman (Belgium) <em>Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species<\/em><\/li><li>14:40 &#8211; Evgeni Ponimaskin (Germany) <em>Amelioration of Tau pathology and memory deficits by targeting serotonin receptors<\/em><\/li><li>14:50 &#8211; Maria-Elena Avale (Argentina)&nbsp;<em>Regulation of tau&nbsp;mis-splicing prevents cognitive and motor deficits in a preclinical model of tauopathy<\/em><\/li><li>15:00 &#8211; Isabelle Landrieu (France) <em>Single domain antibody fragments: new tools for studying Tau as a target for therapy<\/em><\/li><li>15:10 &#8211; Dirk Beher (Switzerland) <em>OGA inhibitors as multimodal drug candidates for tau- and alpha-synucleinopathies<\/em><\/li><li>15:20 &#8211; Norbert Zilka (Slovakia) <em>Tau vaccine AADvac1 trains immune system to produce therapeutic antibodies against disease tau species in Phase II clinical trial<\/em><\/li><li>15:30 &#8211; Philippe Verwaerde (France) <em>EZEPROGIND a new progranulin modulator for the treatment of PSP<\/em><\/li><li>15:40 -Questions<\/li><\/ul>\n\n\n\n<p><em>16:00-16:30 Coffee break<\/em><\/p>\n\n\n\n<p><strong>16:30-17:40 Session 7<\/strong> (Chairs: C. Croft &amp; E. Planel)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>16:30 &#8211; Marco Luppi (Italy) <em>Deep hypothermia stimulates a neuroprotective process reversing the accumulation of hyperphosphorylated tau protein in the rat hippocampus<\/em>  <\/li><li>16:40 &#8211; Emmanuel Planel (Canada) <em>Circadian rhythms of tau phosphorylation and secretion are in antiphase and driven by body temperature<\/em><\/li><li>16:50 Marie-Ange De Fisenne (Belgium) <em>Alzheimer PHF-tau do not spread tau pathology to the brain via the retinotectal pathway after intraocular injection in mouse models <\/em><\/li><li>17:00 &#8211; Cara Croft (UK) Understanding mechanisms to target aggregated tau turnover<\/li><li>17:10 &#8211; Dillon Rinauro (UK)&nbsp;<em>Validating metainference cryo-EM predictions of site-specific posttranslational modifications on tau-microtubule complex stabilit<\/em>y<\/li><li>17:20 Questions<\/li><\/ul>\n\n\n\n<p><strong>17:30 Poster prize<\/strong> <strong>and farewell<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Preliminary programme &#8211; some changes may occur 8:30-9:00 &#8211; Plenary lecture Kenneth Kosik (USA) A Rite of Passage: Tau&#8217;s Route Between And Within Cells 9:00-11:00 &#8211; Session 4 (Chairs: A. Mudher &amp; I. Ferrer) 9:00 &#8211; Eckhard Mandelkow (S. Wegmann) (Germany) Recent insights into Tau seeding and phosphorylation 9:15 &#8211; Susanne Wegmann (Germany) Condensating the&hellip; <a class=\"more-link\" href=\"https:\/\/eurotau.fr\/?page_id=93\">Continue reading <span class=\"screen-reader-text\">Programme Eurotau Oct. 26<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-93","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/93","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/eurotau.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=93"}],"version-history":[{"count":58,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/93\/revisions"}],"predecessor-version":[{"id":477,"href":"https:\/\/eurotau.fr\/index.php?rest_route=\/wp\/v2\/pages\/93\/revisions\/477"}],"wp:attachment":[{"href":"https:\/\/eurotau.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=93"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}