Programme Eurotau Oct. 26

Preliminary programme – some changes may occur

8:30-9:00 – Plenary lecture

Kenneth Kosik (USA) A Rite of Passage: Tau’s Route Between And Within Cells

9:00-11:00 – Session 4 (Chairs: A. Mudher & I. Ferrer)

  • 9:00 – Eckhard Mandelkow (Germany) Recent insights into Tau seeding and phosphorylation
  • 9:15 – Louise Serpell (UK) The role of the core of tau paired helical filaments in AD and other tauopathies
  • 9:25 – Yann Fichou (France) Tau intertwines with cofactors: how it modulates complex phase separation, oligomerization & aggregation properties
  • 9:35 – Susanne Wegmann (Germany) Condensating the interactions of tau
  • 9:45 – Amrit Mudher (UK) Tau aggregation and spread of pathology in¬†Drosophila
  • 9:55 – Isidre Ferrer (Spain) Importance of host tau in tau seeding and spreading in tauopathies
  • 10:05 – Marie-Ange De Fisenne (Belgium) Alzheimer PHF-tau do not spread tau pathology to the brain via the retinotectal pathway after intraocular injection in mouse models
  • 10:15 – Marc Dhenain (France) Induction of tau lesions in amyloid-bearing mice and in primates after inoculation of Alzheimer brain extracts
  • 10:25 – Evgeni Ponimaskin (Germany) Amelioration of Tau pathology and memory deficits by targeting serotonin receptors
  • 10:35 – Diane Hanger (UK) Truncated tau as a model of human tauopathy
  • 10:50 – Questions

11:00-11:30 Coffee break

11:30-13:00 Session 5 (Chairs: D. Hanger & E. Mandelkow))

  • 11:30 – Selected communication
  • 11:40 – Selected communication
  • 11:50 – Selected communication
  • 12:00 – Selected communication
  • 12:10 – Selected communication
  • 12:20 – Selected communication
  • 12:30 – Selected communication
  • 12:40 – Selected communication
  • 12:50 – Questions

13:00-14:30 Lunch & Poster exhibition

14:30-16:00 Session 6 (Chairs: S. Wegmann & M. Dhenain)

  • 14:30 – Karen Duff (UK) Mechanistic underpinnings of selective cellular vulnerability to tauopathy
  • 14:45 – Elodie Leroux (France) Extracellular vesicles and tau seeding among tauopathies
  • 14:55 – Dirk Beher (Switzerland) OGA inhibitors as multimodal drug candidates for tau- and alpha-synucleinopathies15:30 – –
  • 15:10 Norbert Zilka (Slovakia) Tau vaccine AADvac1 trains immune system to produce therapeutic antibodies against disease tau species in Phase II clinical trial
  • 15:25 – Isabelle Landrieu (France) Single domain antibody fragments: new tools for studying Tau as a target for therapy
  • 15:35 – John Sotiropoulos (Portugal) A novel method of spontaneously-released extracellular vesicles isolation from mouse and human brain
  • 15:45 – Marco Luppi (Italy) Deep hypothermia stimulates a neuroprotective process reversing the accumulation of hyperphosphorylated tau protein in the rat hippocampus
  • 15:55 – Questions

16:00-16:30 Coffee break

16:30-17:00 Session FLASH TALKS (Chairs: to be confirmed)

  • 16:30 – Flash talk – selected poster
  • 16:35 – Flash talk – selected poster
  • 16:40 – Flash talk – selected poster
  • 16:45 – Flash talk – selected poster
  • 16:50 – Flash talk – selected poster
  • 16:55 – Flash talk – selected poster

17:00 Poster prize